Lenvima and Keytruda come up short in two cancer types

11 April 2023
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Eisai (TYO: 4523)’s Lenvima (lenvatinib) and Merck & Co’s (NYSE: MRK) Keytruda (pembrolizumab) is a combination that may prove its worth for patients with multiple different cancer types.

But certain patients with advanced melanoma and metastatic colorectal cancer will not be among those to benefit after the combination failed in two Phase III trials.

The companies have announced that they are discontinuing the LEAP-003 trial evaluating the pairing for the first-line treatment of adults with unresectable or metastatic melanoma.

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