Latest Eylea combo failure adds to urgency for Regeneron

28 November 2017

After a 2.7% drop on Monday, shares in Regeneron were down a further 3% at $363.49 by Tuesday lunchtime.

The reason for the slump is likely linked to the decision to drop development of a combination of Eylea (aflibercept) and the angiopoietin2 (Ang2) antibody nesvacumab. The US biotech had been investigating these two treatments under a global collaboration agreement with the German life sciences company Bayer (BAYN: DE), which markets Eylea.

Results from two Phase II trials, named RUBY and ONYX, do not warrant taking the combination into Phase III development, Regeneron announced.

This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Try before you buy

Free

7 day trial access

Take a Free Trial

All the news that moves the needle in pharma and biotech
Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
Receive The Pharma Letter daily news bulletin, free forever.

Become a subscriber

£820

Or £77 per month

Subscribe Now

Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
Daily roundup of key events in pharma and biotech.
Monthly in-depth briefings on Boardroom appointments and M&A news.
Choose from a cost-effective annual package or a flexible monthly subscription

The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK