A major early-stage win in large B-cell lymphoma (LBCL) will take some pressure off the architects of AbbVie’s (NYSE: ABBV) $750 million bet on Danish biotech Genmab (Nasdaq: GMAB).
Top-line results from the EPCORE NHL-1 study show that treatment with the antibody epcoritamab generated an impressive 63.1% overall response rate, with the latest analysis showing a 39% complete response rate.
People in the trial had already been treated with at least two prior lines of anti-lymphoma therapy, including CAR T-cell therapy.
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