Keytruda data encouraging in adjuvant stage IB-IIIA NSCLC
US pharma giant Merck & Co (NYSE: MRK) has announced results from the Phase III KEYNOTE-091 trial investigating Keytruda (pembrolizumab).
The study met one of its dual primary endpoints of disease-free survival (DFS) for the adjuvant treatment of patients with stage IB-IIIA non-small cell lung cancer (NSCLC) following surgical resection regardless of PD-L1 expression.
Based on an interim analysis review conducted by an independent Data Monitoring Committee, adjuvant treatment with Keytruda resulted in a statistically-significant and clinically-meaningful improvement in DFS compared with placebo in the all-comer population of patients with stage IB-IIIA NSCLC.
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