Keytruda combo enters first-line kidney cancer setting in the USA
Merck & Co (NYSE: MRK) has picked up another approval in the USA for its anti-PD-1 therapy Keytruda (pembrolizumab), in combination with the TKI therapy Inlyta (axitinib), against advanced renal cell carcinoma (RCC).
The approval is based on findings from the Phase III KEYNOTE-426 trial, which compared treatment with the combo against treatment with Pfizer’s (NYSE: PFE) Sutent (sunitinib), a current standard of care.
The trial demonstrated significant improvements in overall survival (OS), progression-free survival (PFS) and objective response rate (ORR).
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