Karyopharm shares fly on news of positive Phase III result

3 March 2020

East Coast, USA-based Karyopharm Therapeutics (Nasdaq: KPTI) has announced positive top-line results from the Phase III BOSTON study of Xpovio (selinexor).

Shares in the oncology-focused biotech leapt 70% on Monday, as investors digested results from the study, which examined an Xpovio-based combination therapy as an option against multiple myeloma in a later-line setting.

People with multiple myeloma were given Xpovio plus once-weekly Velcade (bortezomib) and low-dose dexamethasone (SVd), in comparison with standard twice-weekly Velcade plus low-dose dexamethasone (Vd).

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