USA-based Juno Therapeutics (Nasdaq: JUNO) rose 4% in pre-market trading, after it announced three license agreements to advance its program in multiple myeloma using gamma secretase inhibitors (GSIs) in combination with BCMA-directed CAR T cells.
Through its agreement with US pharma major Eli Lilly (NYSE: LLY), Juno will acquire a license to the GSI known as LY3039478, a product candidate that has been studied in 411 patients and healthy volunteers. Through its agreements with OncoTracker and Fred Hutchinson Cancer Research Center, Juno will gain exclusive rights to intellectual property within the field of combinations of GSIs and BCMA-directed engineered T cells.
No other terms from these three transactions were disclosed.
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