Jounce trounced by markets on vopratelimab combo failure

31 August 2022

USA-based Jounce Therapeutics (Nasdaq: JNCE) lost 16% of its stock market value on Tuesday.

This followed the company’s presentation of top-line data from the Phase II SELECT trial evaluating vopratelimab (vopra), Jounce’s inducible costimulator agonist, alongside pimivalimab (pimi) versus pimi alone, in immunotherapy naïve, TISvopra biomarker-selected, second line non-small cell lung cancer (NSCLC) patients.

Pimi is Jounce’s internal investigational PD-1 inhibitor and is also being investigated as monotherapy.

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