Janssen, AbbVie and Roche combo an ASCO highlight

5 June 2018

A combination of Imbruvica (ibrutinib) and Rituxan/MabThera (Rituxan) has shown greater efficacy than the latter drug alone in patients with Waldenström’s macroglobulinemia (WM), a rare and incurable form of non-Hodgkin’s lymphoma (NHL).

The Phase III data featured as an oral presentation at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, was selected for the Best of ASCO 2018 and simultaneously published in the New England Journal of Medicine.

Ibrutinib, a first-in-class Bruton's tyrosine kinase (BTK) inhibitor, is jointly developed and commercialized by Janssen Biotech, part of the Johnson & Johnson (NYSE: JNJ) group, and Pharmacyclics, an AbbVie (NYSE: ABBV) company. It is already approved as a monotherapy in WM.

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