J&J pulls plug on plamotamab to focus on other antibodies
Xencor (Nasdaq: XNCR) has announced it will regain exclusive worldwide rights to plamotamab, a CD20 x CD3 bispecific T-cell engager.
The company had initially developed the drug through Phase I clinical trials in hematologic cancers before entering a collaboration and license agreement with Johnson & Johnson (NYSE: JNJ) in 2021.
J&J has now decided to terminate its rights to plamotamab under this agreement, though it retains rights to develop and commercialize other B-cell targeting CD28 bispecific antibodies, including JNJ-9401 and JNJ-1493.
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