French biotech Ipsen (Euronext: IPN) has entered into an exclusive global licensing agreement with Biomunex Pharmaceuticals to develop BMX-502, a first-in-class T cell engager.
The project will work towards developing innovative options for solid tumors. BMX-502 is a bispecific antibody, developed using Biomunex’s proprietary BiXAb technology, which activates MAIT cells to target the GPC3 tumor antigen.
Scientists at Ipsen are confident that the therapy can overcome challenges associated with traditional T cell engagers, such as dose-limiting toxicity and regulatory T cell activation.
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