Ipsen and Active Biotech discontinue tasquinimod development in prostate cancer
Swedish company Active Biotech (Nasdaq Stockholm: ACTI) and French pharma firm Ipsen (Euronext Paris: IPN) are to discontinue the development of tasquinimod in prostate cancer.
The companies announced top-line results from the 10TASQ10 study, which showed that although the drug reduced the risk of radiographic cancer progression or death compared to placebo, it did not extend overall survival in patients with metastatic, castration-resistant prostate cancer who have not received chemotherapy.
The efficacy results and preliminary safety data do not support positive benefit risk balance in this population, so both companies have decided to discontinue studies in prostate cancer.
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