Ionis Pharmaceuticals (Nasdaq: IONS) rallied 4% pre-market today, after is announced a new collaboration to develop IONIS-FB-LRx for the treatment of complement-mediated diseases, which could earn the company nearly $760 million.
This collaboration with Swiss pharma giant Roche (ROG: SIX) will leverage Ionis' leadership in RNA-targeted therapeutics to develop IONIS-FB-LRx targeting Factor B (FB) for a broad range of diseases. The first indication the two companies will pursue is the treatment of patients with Geographic Atrophy (GA), the advanced stage of dry age-related macular degeneration (AMD). A Phase II study in patients with GA is planned to begin in early 2019.
Details for deal terms
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