Innovent and Lilly's Tyvyt meets endpoint in Phase III lung cancer trial
Chinese biopharma Innovent Biologics (HKEX: 01801) and US pharma major Eli Lilly (NYSE: LLY) have presented results of the Phase III ORIENT-3 study at the American Association for Cancer Research (AACR) Annual Meeting 2021.
ORIENT-3 is evaluating Tyvyt (sintilimab injection) versus docetaxel as a second-line treatment for advanced or metastatic squamous non-small cell lung cancer (sqNSCLC).
"The anti-PD-1 monoclonal antibody sintilimab significantly improved OS"A total of 290 patients whose cancer had progressed following first-line treatment with platinum-based chemotherapy were enrolled.
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