InflaRx decimated as IFX-1 fails in inflammatory skin disorder trial
Germany-headquartered clinical-stage biotech InflaRx (Nasdaq: IFRX) saw its shares crash nearly 92% to $3.06 by close of trading on Wednesday, after the company revealed that IVX-1, its potential treatment for an inflammatory skin disorder, failed to demonstrate statistical significance compared to placebo.
It reported the top-line results of the international SHINE Phase IIb study, investigating the safety and efficacy of IFX-1, a first-in-class anti-human complement factor C5a monoclonal antibody and the firm’s lead candidate, in patients suffering from moderate to severe hidradenitis suppurativa (HS), a painful and debilitating chronic inflammatory skin disease with limited treatment options.
Showed no significant dose response
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