Incyte and Merck provide update on dual immuno-oncology therapy

4 June 2017

Eagerly-anticipated data from an ongoing Phase I/II trial into epacadostat in combination with Keytruda (pembrolizumab) have been released, as the annual meeting of the American Society of Clinical Oncology (ASCO) continues in Chicago.

Data from the trial, which is investigating the dual therapy as a treatment for non-small cell lung cancer (NSCLC), showed an overall response rate (ORR) of 35%.

Epacadostat, under development by US-based Incyte (Nasdaq: INCY), is a selective oral inhibitor of the IDO1 enzyme that stops cancer cells from evading the immune system.

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