Immune checkpoint modulators leading the way in gastric cancer

8 March 2018

Gastric cancer is an area of extreme unmet need where immuno-oncology (I-O) treatments could provide a better survival outcome to patients.

Merck & Co (NYSE: MRK) and two company partnerships, Bristol-Myers Squibb (NYSE: BMY)/Ono Pharmaceuticals (TYO: 4528) and Merck KGaA (MRK: DE)/EMD Serono/Pfizer (NYSE: PFE), are leading the development of immune checkpoint modulators in gastric cancer.

According to analytics company GlobalData, among the 14 Phase II/III and III trials in gastric cancer assessing immune checkpoint modulators, eight are part of currently ongoing trials exploring the potential of immune checkpoint inhibitors in combination with either standard of care chemotherapy or other I-O agents. GlobalData expects this strategy to be practice changing for gastric cancer patients over the next three years.

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