Imfinzi and Eleven's vicinium to enter NMIBC trial
USA-based oncology specialist Eleven Biotherapeutics (Nasdaq: EBIO) has signed an agreement with the US National Cancer Institute (NCI) on the development of the company’s targeted therapeutic, vicinium, in combination with AstraZeneca’s Imfinzi (durvalumab).
The Cooperative Research and Development Agreement will evaluate the activity of vicinium, a single protein molecule composed of an antibody fragment genetically fused to a potent cytotoxic payload, alongside the Anglo-Swedish pharma major’s immune checkpoint inhibitor, in non-muscle invasive bladder cancer (NMIBC).
Under the terms of the agreement, the NCI will conduct a Phase I clinical trial in patients with high-grade NMIBC to evaluate the safety, efficacy, and biological correlates of the vicinium and durvalumab combination therapeutic strategy.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
Free
7 day trial access
- All the news that moves the needle in pharma and biotech
- Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
- Receive The Pharma Letter daily news bulletin, free forever.
Become a subscriber
£820
Or £77 per month
- Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
- Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
- Daily roundup of key events in pharma and biotech.
- Monthly in-depth briefings on Boardroom appointments and M&A news.
- Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
More on this story...
Today's issue
Company Spotlight
More Features in Biotechnology
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze