I-Mab pauses uliledlimab work, shifts to bispecific

7 January 2025

I-Mab (Nasdaq: IMAB) has announced a strategic pivot to prioritize the development of givastomig, a bispecific antibody targeting CLDN18.2 and 4-1BB.

The company’s shares rose by around a fifth following the announcement.

Commenting on the move, which will include pausing work on the firm’s anti-CD73 antibody uliledlimab, chief executive Sean Fu said I-Mab was “building on positive momentum,” after divesting Chinese operations and moving to a USA-based model.

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