ICER final report calls for Vertex restraint and increased pricing transparency for CF drugs

8 June 2018

In its Final Evidence Report and Report-at-a-Glance on cystic fibrosis transmembrane conductance regulator (CFTR) modulators, US health technology accessor the Institute for Clinical and Economic Review, calls for restraint and increased transparency in the pricing of three new cystic fibrosis drugs.

The report includes combination therapies from US biotech firm Vertex Pharmaceuticals (Nasdaq: VRTX): Symdeko (tezacaftor/ivacaftor); and Orkambi (lumacaftor/ivacaftor) and monotherapy Kalydeco (ivacaftor) for the treatment of CF.

Vertex’s revenues from its CF portfolio are expected to reach $2.1 billion this year, though Bloomberg estimates suggest that they could be $4.2 billion by 2020.

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