GlobeImmune's GS-4774 flops in Phase II trial in HBV patients
US biotech firm GlobeImmune (Nasdaq: GBIM) today announced disappointing top- line results from the GS-4774 Phase II study in patients with chronic hepatitis B on long term viral suppression with an oral antiviral treatment.
GlobeImmune shares, which closed up 11.65% at $8.24 on Tuesday, plunged nearly 50% to $4.12 shortly after markets opened this morning. GlobeImmune is developing GS-4774 with Gilead Sciences (Nasdaq: GILD) under an agreement signed in 2011 (The Pharma Letter October 25, 2011).
Study details
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