Gilead unblinds Phase III study of Zydelig
US biotech giant Gilead Sciences (Nasdaq: GILD) has announced it is unblinding a Phase III study of Zydelig (idelalisib) following a recommendation by an independent data monitoring committee.
The decision was made after an interim analysis revealed greater progression-free survival and overall survival in patients who took Zydelig in combination with Roche’s (ROG: SIX) Rituxan (rituximab) and Teva’s (NYSE: TEVA) Treanda (bendamustine).
In the study 416 adults, with previously treated chronic lymphocytic leukaemia (CLL) were randomized to six cycles of Rituxan and Treanda over 24 weeks in combination with either Zydelig or a placebo taken twice daily.
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