US biotech major Gilead Sciences (Nasdaq: GILD) has reported high rates of virologic response at 12 weeks across all six genotypes of hepatitis C in trials of its drug Sovaldi (sofosbuvir) and velpatasvir.
The ASTRAL-1, ASTRAL-2 and ASTRAL-3 studies consisted of 1,035 patients with hepatitis C infection who received treatment with Sovaldi and velpatasvir for 12 weeks. The company found that 21% of the patients in the trials had compensated cirrhosis, and 28% had failed prior treatments.
Norbert Bischofberger, executive vice president of R&D and chief scientific officer at Gilead, said that the results from the ASTRAL studies "demonstrate that a 12-week course of therapy with the first fixed-dose combination of two pan-genotypic compounds can provide high cure rates for patients with all HCV genotypes."
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze