US biotech Gilead Sciences (Nasdaq: GILD) has presented new data showing positive signs on treatments it is developing for the liver conditions nonalcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC).
The findings, which were presented at the International Liver Congress 2016 in Barcelona, Spain, support the continuation of studies of simtuzumab, GS-4997 and GS-9674, investigational compounds for the treatment of NASH and PSC.
NASH is a serious liver disease resulting from metabolic dysfunction that is associated with steatosis – fat within the liver – along with inflammation and fibrosis, which may progress to cirrhosis. By 2020, NASH-related cirrhosis is expected to become the leading indication for liver transplantation.
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