Geron in up to $935 million deal with Janssen for imetelstat

14 November 2014

US biotech firm Geron Corp (Nasdaq: GERN) has entered into an exclusive worldwide license and collaboration agreement with Janssen Biotech, a subsidiary of US health care giant Johnson & Johnson (NYSE: JNJ), to develop and commercialize, imetelstat, Geron's telomerase inhibitor product candidate, for oncology, including hematologic malignancies, and other human therapeutics uses, worth a potential of $935 million to Geron.

Geron’s jumped 32% to $3.05 in after-hours trading following the announcement on Thursday.

Imetelstat is a modified oligonucleotide that is currently in early phase clinical development for myelofibrosis (MF) and may have activity in other hematologic myeloid malignancies such as myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML).

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