Fremanezumab meets goals as a prophylactic treatment for migraine

28 January 2020

Japanese drugmaker Otsuka Pharmaceutical (TYO: 4578) has announced positive preliminary results from two, Phase II/III trials for fremanezumab as a prophylactic migraine drug.

Fremanezumab is an anti-calcitonin gene-related peptide (CGRP) monoclonal antibody. It is administered as a subcutaneous injection for the prevention of chronic and episodic migraine. Fremanezumab is under development in Japan by Otsuka, which entered into an exclusive license agreement with Teva Pharmaceutical Industries (NYSE: TEVA) in May 2017 for development and sales in Japan.

In June last year, Teva gained European approval for the drug, which carries the trade name Ajovy. Ajovy received US Food and Drug Administration approval for the preventive treatment of migraine in adults in September 2018.

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