The UK National Institute for Health and Care Excellence (NICE) has issued its Final Appraisal Determination (FAD) recommending the use of four out of six disease-modifying therapies in relapsing-remitting multiple sclerosis.
Those recommended for use on the UK’s National Health Service (NHS) are German drugmaker Merck KGaA’s (MRK: DE) Rebif (interferon β-1a), Biogen’s (Nasdaq: BIIB) Avonex (interferon β-1a), Novartis’ (NOVN: VX) Extavia (interferon β-1b) and Teva Pharmaceutical Industries’ (NYSE: TEVA) Copaxone (glatiramer acetate).
These companies must provide the drugs with the discounts agreed in the patient access schemes. In the preliminary guidance from the NICE, issued in December 2017, only the Novartis drug had been recommended for usage, but further negotiations have since taken place, leading to the additional recommendations.
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