First tumor-agnostic nod for Tafinlar plus Mekinist in the USA

23 June 2022

Swiss pharma giant Novartis (NOVN: VX) has received an Accelerated Approval in the USA for its combination BRAF/MEK inhibitor therapy, for certain biomarker-defined tumors.

The nod makes the Tafinlar (dabrafenib) plus Mekinist (trametinib) treatment the first and only therapy of its kind available in a tumor-agnostic indication, for solid tumors carrying the BRAF V600E mutation.

This mutation is known to drive tumor growth in more than 20 different types of cancer, and the decision from the US Food and Drug Administration will bring a new treatment option for people with no alternatives.

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