First-in-class blood cancer med could soon face regulatory test

22 November 2023

It has been a challenging week for Germany's MorphoSys (FSE: MOR), with the firm’s share price falling as much as 40% in the last five days.

Most of the share sell-off came on Tuesday, after the company announced mixed results from the Phase III MANIFEST-2 study of the BET blocker pelabresib.

While the trial met its primary endpoint, a reduction in spleen volume, the myelofibrosis candidate did not improve symptoms enough for key secondary endpoints to be met.

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