FDA lifts clinical hold on Halozyme's PEGPH20 pancreatic cancer trial

22 September 2014

US biotech firm Halozyme Therapeutics (Nasdaq: HALO) says the US Food and Drug Administration has removed the clinical hold on patient enrollment and dosing of PEGPH20 in SWOG's ongoing Phase Ib/II clinical trial (S1313).

Notwithstanding, the company’s shares dipped 2.5% to $9.55 in mid-morning trading today, having slumped more than 23% to $8.90 on the original announcement of the clinical hold (The Pharma Letter April 9).

The trial is designed to evaluate Halozyme's investigational drug PEGPH20 (PEGylated recombinant human hyaluronidase) in combination with modified FOLFIRINOX chemotherapy (mFOLFIRINOX) in patients with metastatic pancreatic adenocarcinoma.

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