Top-line results from the Phase IIIb PONENTE study show that 62% of people with severe asthma were able to stop using oral corticosteroids (OCS) when treated with Fasenra (benralizumab).
AstraZeneca (LSE: AZN) said the interleukin (IL)-5 receptor binding biologic eliminated the use of maintenance OCS use in people with a broad range of blood eosinophil counts.
The trial met both primary endpoints, with 81% of people achieving complete elimination or a reduction in daily use of OCS treatment to 5mg or less, when further reduction was not possible due to adrenal insufficiency.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze