ESMO 2023: Positive interim data for Imfinzi in stomach cancer

20 October 2023

Britain’s largest drugmaker, AstraZeneca (LSE: AZN), has reported positive results from a planned interim analysis of the Phase III MATTERHORN trial.

Presented at the annual congress of the European Society for Medical Oncology (ESMO), the results show the impact of treatment with the checkpoint blocker Imfinzi (durvalumab), plus chemotherapy.

The interim analysis shows a statistically-significant and clinically-meaningful improvement in the key secondary endpoint of pathologic complete response, versus neoadjuvant chemotherapy alone.

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