Endocyte in-licenses Phase III-ready PSMA-targeted radioligand therapy

2 October 2017

US biopharma firm Endocyte has executed an exclusive worldwide license of PSMA-617 from ABX GmbH.

Endocyte intends to move quickly into Phase III development of 177Lu-PSMA-617, a radioligand therapeutic (RLT) that targets the prostate-specific membrane antigen (PSMA), present in around 80% of patients with metastatic castration-resistant prostate cancer (mCRPC).

"This transaction is transformational to Endocyte, accelerating our path to commercialization. 177Lu-PSMA-617 has the potential to be the first-in-class RLT to address both bone and soft tissue disease, and it is profoundly important to the many patients suffering from mCRPC," said Mike Sherman, president and chief executive of Endocyte.

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