Eikon Therapeutics gains rights to batch of clinical-stage oncology assets

California, USA-based biotech start-up Eikon Therapeutics has acquired exclusive rights to multiple early- to mid-stage assets, leveraging its proprietary Single Molecule Tracking (SMT) technology to drive strategic decisions around its new drug pipeline.

Eikon noted that it has successfully completed three transactions, including the acquisition of global rights to develop and commercialize clinical-stage Toll-like receptor 7 and 8 (TLR7/8) agonist immune modulators from Seven and Eight Biotherapeutics Corp that have been tested in over 150 patients with advanced, refractory, solid tumors. These immune modulators have shown tolerable safety and activity both as monotherapy and in combination with PD-(L)1 inhibitors.

The company has also licensed a portfolio of PARP1-selective inhibitors invented by Impact Therapeutics and intended to improve upon existing unselective dual PARP1/2 inhibitory agents in cancer treatment. Eikon and Impact plan to file a US Investigational New Drug (IND) Application for this program by the end of the third quarter of 2023.