Discount checkpoint blocker aims to disrupt market

13 May 2021

New York’s Checkpoint Therapeutics (Nasdaq: CKPT) has finished enrolling patients in a registration-enabling trial of its experimental checkpoint blocker cosibelimab.

The trial evaluates the immunotherapy as an option for people with metastatic cutaneous squamous cell carcinoma (cSCC), and has a primary efficacy endpoint of confirmed objective response rate (ORR).

Checkpoint believes its candidate is a potential best-in-class PD-L1 blocker, with a unique mechanism of action which removes the suppressive effects of PD-L1 on certain anti-tumor components of the immune system.

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