Data shows benefit of Xgeva in multiple myeloma

4 June 2017

US biotech Amgen (Nasdaq: AMGN) on Sunday announced new data from the Xgeva (denosumab) Phase III ‘482 study, the largest international multiple myeloma trial ever conducted.

The study met its primary endpoint, demonstrating that Xgeva is non-inferior to zoledronic acid in delaying the time to first on-study skeletal-related event in patients with multiple myeloma.

"Up to 40% of patients remain untreated for the prevention of bone complications, and the percentage is highest among patients with renal impairment at the time of diagnosis, underscoring the need for alternative treatment options"

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