Japanese pharma major Daiichi Sankyo (TYO: 4568) has pulled the plug on development of an inhaled formulation of nafamostat, dubbed DS-2319, as a treatment for COVID-19.
The firm had been developing nafamostat in the belief that it might help combat the disease by blocking membrane fusion between the envelope of the virus that causes COVID-19 and the host plasma cell membrane.
Based on the results from a Phase I trial, initiated in March 2021, as well as ongoing non-clinical studies, the company said it would not continue development at this time.
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