Confo inks deals with Daiichi Sankyo on CNS diseases

30 March 2023

Belgian G-protein coupled receptor (GPCR) company Confo Therapeutics revealed today that it has entered a collaboration agreement with Japan’s Daiichi Sankyo (TYO: 4568) for the discovery and development of small molecule agonists against an undisclosed target associated with CNS diseases.

The news comes just weeks after Confo signed a deal potentially worth more than $600 million with US pharma major Eli Lilly (NYSE: LLY) for its clinical stage CFTX-1554 and back-up compounds.

The accord provides for Confo to lead the discovery process deploying its GPCR platform to generate lead series of small molecule compounds. Daiichi Sankyo has an exclusive option to acquire a worldwide exclusive license for the resulting compounds and advance them towards clinical development and commercialization. In return, Confo has the potential to receive upfront payments, development and commercial milestones totaling 168 million euros ($182 million) and royalties.

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