Columvi combination hits the mark in R/R DLBCL
Roche’s (ROG: SIX) CD20xCD3 T-cell engaging bispecific antibody Columvi (glofitamab) has met the primary endpoint of overall survival in relapsed or refractory diffuse large B-cell lymphoma in the Phase III STARGLO study.
The study demonstrated that people with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), who have received at least one prior line of therapy and are not candidates for autologous stem cell transplant, lived longer when treated with Columvi (glofitamab) alongside gemcitabine and oxaliplatin (GemOx) versus Roche’s older therapy MabThera/Rituxan (rituximab) with GemOx.
"People with this aggressive lymphoma facing relapse or progression after initial treatment have limited options – particularly those who are ineligible for stem cell transplant"Safety of the combination appeared consistent with the known safety profiles of the individual medicines. The data will be submitted to health authorities and shared at an upcoming medical meeting.
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