Chugai strikes again in Japan with PiaSky launch

23 May 2024
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Roche’s (ROG: SIX) Japan-based majority-owned company Chugai (TYO: 4519) has launched PiaSky for injection 340mg (crovalimab), a pH-dependent binding humanized anti-complement (C5) monoclonal antibody for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), in the Asian country.

PiaSky was approved by the Ministry of Health, Labor and Welfare (MHLW) on March 26 this year, and it has now been listed on the national health insurance reimbursement price list.

"This is the fifth launch in Japan of a Chugai-originated antibody medicine"Unlike conventional antibodies that bind to an antigen only once, crovalimab has been engineered to bind to the antigen repeatedly, enabling low dose subcutaneous administration every four weeks.

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