Chiome Bioscience and ProBioGen link up on antibody production

5 October 2017

German contract development and manufacturing company ProBioGen and Japan-based biotech company Chiome Bioscience (TYO: 4583) today jointly announced signing a service and license agreement.

Under the agreement ProBioGen will apply its enhanced cancer cell-killing technology GlymaxX® to LIV-1205, a clinical candidate in an antibody manufacturing program for Chiome.

Specifically, ProBioGen will develop a stable GlymaxX cell line, followed by process development and GMP manufacturing of the ADCC-enhanced cancer stem cell antibody, which will be optimized for enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) cancer cell-killing activity.

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