US biotech firm Celgene (Nasdaq: CELG) says it will acquire privately-held company Delinia, which is developing novel therapeutics for autoimmune diseases.
The transaction expands Celgene’s inflammation and immunology pipeline through the acquisition of Delinia’s lead program, DEL106, as well as related second generation programs. DEL106 is a novel IL-2 mutein Fc fusion protein designed to preferentially upregulate regulatory T cells (Tregs), immune cells that are critical to maintaining natural self-tolerance and immune system homeostasis. Augmenting Tregs as a means of restoring immune system balance has the potential to benefit patients with a variety of autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.
Deal worth a potential $775 million
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