Moving into Phase III, Cartesian data show momentum

4 December 2024

Cartesian Therapeutics (Nasdaq: RNAC) has announced updated results from a Phase IIb trial of Descartes-08 for generalized myasthenia gravis.

The results, outlined during the Cell Therapy for Autoimmune Disease Summit in Philadelphia, highlight improved patient outcomes, with months to go until the Phase III AURORA study.

The mid-stage research investigates the firm’s mRNA-engineered CAR-T cell therapy targeting B-cell maturation antigen (BCMA), administered without preconditioning chemotherapy.

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