Bristol-Myers Squibb to evaluate new dual therapy with immuno-oncology specialists Apexigen

12 April 2017

Bristol-Myers Squibb (NYSE: BMY) and Apexigen are to conduct a clinical trial into a new dual therapy in immuno-oncology, evaluating Opdivo (nivolumab) in combination with Apexigen’s APX005M in patients with advanced solid tumors.

Apexigen, an American biotech firm specializing in immuno-oncology, has developed APX005M using its proprietary antibody discovery platform, called APXiMAB.

APX005M is designed to activate CD40, an immune receptor involved in the activation of both innate and adaptive immune responses against cancer.

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