Bristol-Myers amends licensing deal with Five Prime
US pharma major Bristol-Myers Squibb (NYSE: BMY) has entered into an exclusive worldwide license and collaboration agreement for the development and commercialization of Five Prime Therapeutics’ (Nasdaq: PFRX) colony stimulating factor 1 receptor (CSF1R) antibody program, including FPA008 which is in Phase 1 development for immunology and oncology indications.
This agreement replaces the companies' existing clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of combining Opdivo (nivolumab), Bristol-Myers Squibb's programmed-death 1 (PD-1) immune checkpoint inhibitor, with FPA008 in six tumor types (The Pharma Letter November 24, 2014).
Deal worth a potential $1.74 billion to Five Prime
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