US pharma giant Pfizer (NYSE: PFE) has been handed a boost in its development of its ALK/ROS1 tyrosine kinase inhibitor, lorlatinib.
The biomarker-driven drug has been granted Breakthrough Therapy designation by the US Food and Drug Administration (FDA) as a potential treatment for patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC), previously treated with one or more ALK inhibitors.
Lorlatinib is backed by data from a Phase I/II study and a Phase III trial has now begun enrolling patients.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze