Boehringer bills itself as a leader with Wnt/β-catenin pathway blocker

1 April 2019

Privately-owned German pharma major Boehringer Ingelheim has boasted that it is the first company to develop a potent inhibitor targeting a critical node of the Wnt/β-catenin pathway.

The firm has been showing off its work in lung and gastrointestinal (GI) cancer at the 2019 American Association for Cancer Research (AACR) Annual Meeting, March 29 to April 3, in Atlanta.

Candidates that feature in AACR presentations include the LRP5/6 antagonist, BI 905677, which is undergoing a Phase I trial in patients with advanced cancers.

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