Biden reforms lead to Alnylam Amvuttra decision

28 October 2022

Alnylam (Nasdaq: ALNY) has announced that it will not presently be taking its drug Amvuttra (vutrisiran) into a Phase III trial for Stargardt disease.

Amvuttra has already won approval in the USA for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults. It has also been approved for transthyretin type familial amyloidosis with polyneuropathy in Japan.

The US RNAi therapeutics company had been due to take the drug into a Phase III study in Stargardt disease, a rare genetic eye disease that happens when fatty material builds up on the macula, late this year.

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