BeiGene presents positive results for novel checkpoint inhibitor

10 December 2021

Sino-American biotech BeiGene (Nasdaq: BGNE) has announced positive results from the Phase III RATIONALE 309 trial of tislelizumab, a checkpoint blocker.

The immuno-oncology candidate, which is specifically designed to minimize binding to FcγR on macrophages, is being studied as a monotherapy and in combination with other therapies in a broad range of cancers.

In RATIONALE 309, the candidate is being compared with placebo in combination with chemotherapy as a first-line treatment for patients with recurrent or metastatic nasopharyngeal cancer (RM-NPC).

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