Baxalta sues Chugai over hemophilia A drug patent

12 May 2016

Japanese drugmaker Chugai Pharmaceutical (TYO: 4519) has revealed that a lawsuit was filed against the company at the Tokyo District Court by US biotechnology firm Baxalta (NYSE: BXLT).

It is alleged by Baxalta that the new drug candidate under development by Chugai, which is majority owned by Swiss pharma giant Roche (ROG: SIX), for the treatment of hemophilia A, emicizumab (development code: ACE910), is infringing one of its patent (patent number 4313531) and thus it filed for an injunction against manufacture, usage, transfer, exportation, and offer of any transfer regarding emicizumab, and requested cessation.

ACE910, currently in late-stage clinical trials by Roche and Chugai, is a double-headed (bispecific) antibody which simultaneously binds to both Factor IXa and Factor X and mimics the effect of Factor VII, the usual treatment for hemophilia A.

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